Profhilo contains a mixture of high and low molecular weight hyaluronic acid molecules. The concentration of hyaluronic acid in Profhilo is 64mg/2ml (or 32mg/ml)- higher than the concentration of hyaluronic acid in dermal fillers like Juvedem's Voluma and Restylae's Perlane (both contain 20mg/ml). You might be familiar with hyaluronic acid- it is a familiar feature in dermal fillers and skincare for its hydrating prowess. In Profhilo, the low molecular weight hyaluronic acid allows for a slow and sustained release of hyaluronic acid which causes bioremodelling and reduced inflammation. The high molecular weight hyaluronic acid reinforces the framework and scaffolding of hyaluronic acid in the skin for the lifting (i.e. bioremodelling) effect3,4.