| Customization: | Available |
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| Certification: | FDA, CE |
| Disinfection: | Disinfection |
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Profhilo is the first BDDE-free injectable Hyaluronic Acid for hydrating skin and treating skin laxity.
With one of the highest concentrations of HA in the market (64mg/2cc), the stabilised HA lasts in the skin for about 28 days.
Profhilo works because of 2 types of hyaluronic acid: L-HA and H-HA. This hybrid of HA allows hyaluronic acid to be released slowly and lasts longer allowing bioremodeling to take place.
L-HA as a hybrid complex is released slowly and hydrates your skin, providing the Hydro effect.
H-HA provides a stable HA architecture in the dermis that allows volumetric replacement, giving the Lift effect.
During this time, the slow release of HA kickstarts stimulation of 4 different types of collagen and elastin.
Histologically, the expression levels of type I and type III collagen and type IV and VII collagen in keratinocytes are increased.
Profilo treatment is considered a bioremodelling therapy. This unique stabilized hybrid cooperative HA complex has different biological properties when compared to monotherapy with either High or Low molecular weight HAs. The resistance to enzymatic degradation, slow release action and biocompatibility properties makes it different from the standard HAs in today's market.
The slow release action of Profhilo treatment provides hydration at the epidermal layer and enhances volume within the dermal architecture. There is an up-regulation of the 4 main types of collagen. There is an increased expression of type I and III collagen in fibroblasts and type IV and VII in keratinocytes. In addition, elastin and natural HAs within the skin are stimulated. This multimodal effect increases hydration, elasticity and lifting effect of the skin.
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